PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-202013	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]benzamide	2222110-98-5	CRBN	AR	Inquiry
Molecular Weight: 778.31 Molecular Formula: C42H44ClN7O6 Boiling Point: 984.6±65.0°C at 760 Torr Density: 1.44±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202014	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]methyl]-1-piperazinyl]benzamide	2222111-86-4	CRBN	AR	Inquiry
Molecular Weight: 792.34 Molecular Formula: C43H46ClN7O6 Boiling Point: 989.4±65.0°C at 760 Torr Density: 1.42±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202015	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-4-piperidinyl]-1-piperazinyl]benzamide	2756442-94-9	CRBN	AR	Inquiry
Molecular Weight: 806.36 Molecular Formula: C44H48ClN7O6 Boiling Point: 995.4±65.0°C at 760 Torr Density: 1.41±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202016	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]carbonyl]benzamide	2756442-95-0	CRBN	AR	Inquiry
Molecular Weight: 806.32 Molecular Formula: C43H44ClN7O7 Boiling Point: 1014.1±65.0°C at 760 Torr Density: 1.46±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202017	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[[4-[[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]methyl]-1-piperazinyl]carbonyl]benzamide	2756442-97-2	CRBN	AR	Inquiry
Molecular Weight: 820.35 Molecular Formula: C44H46ClN7O7 Boiling Point: 1018.5±65.0°C at 760 Torr Density: 1.44±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202018	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-4-piperidinyl]-1-piperazinyl]carbonyl]benzamide	2756442-96-1	CRBN	AR	Inquiry
Molecular Weight: 834.37 Molecular Formula: C45H48ClN7O7 Boiling Point: 1024.2±65.0°C at 760 Torr Density: 1.43±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202019	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[[4-[[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-4-piperidinyl]methyl]-1-piperazinyl]carbonyl]benzamide	2756442-98-3	CRBN	AR	Inquiry
Molecular Weight: 848.39 Molecular Formula: C46H50ClN7O7 Boiling Point: 1028.9±65.0°C at 760 Torr Density: 1.41±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202020	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-1-piperazinyl]-1-piperidinyl]benzamide	2222112-14-1	CRBN	AR	Inquiry
Molecular Weight: 806.36 Molecular Formula: C44H48ClN7O6 Boiling Point: 995.4±65.0°C at 760 Torr Density: 1.41±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202021	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[[4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]benzamide	2222110-35-0	CRBN	AR	Inquiry
Molecular Weight: 820.39 Molecular Formula: C45H50ClN7O6 Boiling Point: 1000.4±65.0°C at 760 Torr Density: 1.39±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202022	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[2-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-2-azaspiro[3.3]hept-6-yl]-1-piperazinyl]benzamide	2756442-99-4	CRBN	AR	Inquiry
Molecular Weight: 818.38 Molecular Formula: C45H48ClN7O6 Density: 1.44±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202023	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[[2-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-2-azaspiro[3.3]hept-6-yl]methyl]-1-piperazinyl]benzamide	2756443-00-0	CRBN	AR	Inquiry
Molecular Weight: 832.39 Molecular Formula: C46H50ClN7O6 Density: 1.42±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202024	N-((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-4-(4-(6-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)-6-azaspiro[3.4]octan-2-yl)piperazin-1-yl)benzamide	2756580-78-4	CRBN	AR	Inquiry
Molecular Weight: 832.39 Molecular Formula: C46H50ClN7O6 Density: 1.42±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202025	N-((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-4-(4-((6-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)-6-azaspiro[3.4]octan-2-yl)methyl)piperazin-1-yl)benzamide	2756580-79-5	CRBN	AR	Inquiry
Molecular Weight: 846.43 Molecular Formula: C47H52ClN7O6 Density: 1.41±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202026	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[3-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azaspiro[5.5]undec-9-yl]-1-piperazinyl]benzamide	2756443-01-1	CRBN	AR	Inquiry
Molecular Weight: 874.48 Molecular Formula: C49H56ClN7O6 Density: 1.38±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202027	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[2-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-2-azaspiro[3.5]non-7-yl]-1-piperazinyl]benzamide	2756443-02-2	CRBN	AR	Inquiry
Molecular Weight: 846.43 Molecular Formula: C47H52ClN7O6 Density: 1.41±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202028	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]-7-azaspiro[3.5]non-7-yl]benzamide	2756443-03-3	CRBN	AR	Inquiry
Molecular Weight: 777.32 Molecular Formula: C43H45ClN6O6 Boiling Point: 992.3±65.0°C at 760 Torr Density: 1.41±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202029	N-[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]-3-azaspiro[5.5]undec-3-yl]benzamide	2756443-04-4	CRBN	AR	Inquiry
Molecular Weight: 805.38 Molecular Formula: C45H49ClN6O6 Boiling Point: 1002.9±65.0°C at 760 Torr Density: 1.38±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202030	N-[(1S,3S)-3-(3-Chloro-4-cyanophenoxy)-2,2-dimethylcyclobutyl]-4-[4-[[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-4-piperidinyl]methyl]-1-piperazinyl]benzamide	2756443-05-5	CRBN	AR	Inquiry
Molecular Weight: 792.34 Molecular Formula: C43H46ClN7O6 Boiling Point: 1006.2±65.0°C at 760 Torr Density: 1.43±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202031	N-[trans-3-(3-Chloro-4-cyanophenoxy)cyclobutyl]-4-[4-[[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-4-piperidinyl]methyl]-1-piperazinyl]benzamide	2757424-01-2	CRBN	AR	Inquiry
Molecular Weight: 764.28 Molecular Formula: C41H42ClN7O6 Boiling Point: 1014.5±65.0°C at 760 Torr Density: 1.46±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.
	BPL-202032	N-[trans-3-(4-Cyano-3-fluorophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-4-piperidinyl]methyl]-1-piperazinyl]benzamide	2756443-07-7	CRBN	AR	Inquiry
Molecular Weight: 803.94 Molecular Formula: C45H50FN7O6 Boiling Point: 973.6±65.0°C at 760 Torr Density: 1.38±0.1 g/cm3 Description: It is a potent and orally bioavailable proteolysis targeting chimera degrader of androgen receptor for the treatment of prostate cancer.