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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
RSS0628 BPL-201913 RSS0628 2769850-25-9

CRBN

AAK1
AURKA
CAMKK1
CDK4
CDK6
LIMK2
NEK9
PTK2B
STK17A
STK17B
ULK1
ULK3
Wee1

Inquiry

Molecular Weight: 868.98

Molecular Formula: C42H44N8O9S2

Density: 1.444±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

RSS0680 BPL-201914 RSS0680 2769753-48-0

VHL

AAK1
CDK1
CDK16
CDK17
CDK2
CDK4
CDK6
CDK7
EIF2AK4
GAK
LATS1
LIMK2
MAPK6
MAPKAPK5
MARK2
MARK4
MKNK2
NEK9
RPS6KB1
SIK2
SNRK
STK17A
STK17B
STK35
ULK1
Wee1

Inquiry

Molecular Weight: 1021.35

Molecular Formula: C52H64N10O6S3

Density: 1.322±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SB1-G-181 BPL-201915 SB1-G-181 2570916-88-8

CRBN

ABL1
ABL2
AURKA
BLK
CSK
CSNK1E
FYN
LATS1
LCK
LIMK1
MAP2K5
Src

Inquiry

Molecular Weight: 869.98

Molecular Formula: C46H51N11O7

Density: 1.49±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SB1-G-187 BPL-201916 SB1-G-187 2769753-18-4

CRBN

ABL1
ABL2
BLK
CDK14
CDK17
CDK5
CDK6
COQ8A
EPHA1
EPHA2
FER
FYN
GAK
IRAK1
LCK
LYN
MAP3K1
MAP3K20
MAP3K7
MAP4K2
MAP4K5
p38alpha
PDK1
PDK2
PDK3
RIPK1
RIPK2
Src
STK10
TAOK3
YES1

Inquiry

Molecular Weight: 1022.05

Molecular Formula: C52H54F3N9O10

Density: 1.40±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SB1-G-190 BPL-201917 SB1-G-190 2769850-23-7

CRBN

AAK1
AURKA
BMP2K
GSK3A
GSK-3beta

Inquiry

Molecular Weight: 844.93

Molecular Formula: C43H48N12O7

Density: 1.414±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SB1-G-192-1 BPL-201918 SB1-G-192-1 2769753-12-8

CRBN

ABL1
ABL2
AURKA
BLK
CSK
EPHA3
EPHB6
FYN
GAK
LCK
LIMK2
NLK
p38alpha
PDK1
PKMYT1
SIK2
Src
TNK2
Wee1
YES1

Inquiry

Molecular Weight: 897.77

Molecular Formula: C44H42Cl2N8O9

Density: 1.431±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SB1-G-194 BPL-201919 SB1-G-194 2769850-22-6

CRBN

AAK1
AURKA
AURKB
CDK6
CDK9
FGFR2
STK17A
TTK

Inquiry

Molecular Weight: 832.92

Molecular Formula: C44H48N8O9

Density: 1.387±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SB1-G-200 BPL-201920 SB1-G-200 2570916-95-7

CRBN

ABL1
ABL2
BLK
CSK
CSNK1E
FYN
LATS1
LCK
LIMK1
MAP2K5
Src

Inquiry

Molecular Weight: 883.02

Molecular Formula: C48H54N10O7

Density: 1.45±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SK-3-87 BPL-201921 SK-3-87 2769753-27-5

CRBN

AAK1
AURKA
BLK
CDK12
CDK17
CDK2
CDK5
CDK7
CDK9
FER
ITK
LCK
LIMK2
PTK2B
Wee1

Inquiry

Molecular Weight: 975.53

Molecular Formula: C46H55ClN10O10S

Density: 1.395±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SK-3-89 BPL-201922 SK-3-89 2769753-36-6

CRBN

AAK1
AURKA
BLK
CDK12
CDK17
CDK2
CDK4
CDK5
CDK6
CDK7
CDK9
FER
ITK
LCK
LIMK2
PTK2B
STK10
Wee1

Inquiry

Molecular Weight: 975.53

Molecular Formula: C46H55ClN10O10S

Density: 1.395±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SK-3-91 BPL-201923 SK-3-91 2769753-23-1

CRBN

AAK1
ABL1
ABL2
AKT2
AKT3
AURKA
AURKB
BCKDK
BLK
BMP2K
BMPR1A
BUB1
BUB1B
CDC7
CDK10
CDK12
CDK13
CDK14
CDK16
CDK17
CDK18
CDK2
CDK4
CDK5
CDK6
CDK7
CDK9
COQ8A
CSK
CSNK1D
EPHB2
EPHB4
FAK
FER
FYN
GAK
HIPK1
ITK
LATS1
LCK
LIMK1
LIMK2
LRRK2
MAP3K1
MAP3K11
MAP3K12
MAP3K21
MAP4K1
MAP4K3
MAPK6
MAPK7
MARK2
MARK4
MAST3
MKNK2
NEK2
PDK3
PLK1
PLK4
PRAG1
PRKAA1
PRKAA2
PTK2B
PTK6
RIOK2
RPS6KA1
RPS6KA6
RPS6KB1
RPS6KC1
SBK1
SIK2
Src
STK17A
STK17B
STK32C
STK33
STK40
TEC
TGFBR1
TNK1
TNK2
TRIB3
TRPM7
TTK
UHMK1
ULK1
ULK3
Wee1
YES1

Inquiry

Molecular Weight: 887.42

Molecular Formula: C42H47ClN10O8S

Density: 1.430±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

SK-3-93 BPL-201924 SK-3-93 2769753-33-3

CRBN

AAK1
ABL2
AURKA
BLK
BMP2K
CDK12
CDK13
CDK17
CDK2
CDK4
CDK5
CDK6
CDK7
CDK9
FER
GAK
ITK
LCK
LIMK2
PRKAA1
PTK2B
RPS6KA1
Src
Wee1

Inquiry

Molecular Weight: 887.42

Molecular Formula: C42H47ClN10O8S

Density: 1.430±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

TL13-178 BPL-201925 TL13-178

CRBN

CDK4
LIMK1
MAP3K20
MAST3
p38alpha

Inquiry

Molecular Weight: 962.99

Molecular Formula: C49H49F3N10O8

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

TL13-97 BPL-201926 TL13-97 2769850-17-9

CRBN

AAK1
ABL2
AURKA
AURKB
BLK
BUB1B
CDK13
CDK17
CDK2
CDK4
CDK5
CDK6
CDK7
CDK9
FER
ITK
LCK
LIMK1
LIMK2
MAP3K11
MARK4
PLK4
PRKAA1
RPS6KA1
Src
STK10
STK38
TEC
TNK2
ULK1
ULK3
Wee1

Inquiry

Molecular Weight: 984.02

Molecular Formula: C50H50FN11O10

Boiling Point: 1106.4±65.0°C at 760 Torr

Density: 1.45±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

TM-04-168-03 BPL-201927 TM-04-168-03 2769850-14-6

CRBN

PIP4K2A
PIP4K2B
PIP4K2C

Inquiry

Molecular Weight: 805.81

Molecular Formula: C43H35N9O8

Boiling Point: 1132.3±65.0°C at 760 Torr

Density: 1.498±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

WH-10417-099 BPL-201928 WH-10417-099 2769753-42-4

CRBN

CSNK1A1
CSNK1D
CSNK1E
GSK3A
GSK-3beta
LIMK2
MAP3K1
MINK1
PAK4
STK10
STK17B
STK35
STK4

Inquiry

Molecular Weight: 1039.18

Molecular Formula: C52H62N8O13S

Density: 1.43±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

WH-9533-153 BPL-201929 WH-9533-153 2353563-15-0

CRBN

CDK14
CSNK1D
GSK3A
GSK-3beta
NUAK1
PIM2
STK17B
STK4

Inquiry

Molecular Weight: 1057.17

Molecular Formula: C52H61FN8O13S

Density: 1.45±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

ZNL-03-127 BPL-201930 ZNL-03-127 2769850-08-8

CRBN

BLK
LIMK1
LIMK2
STK17A
TNK2

Inquiry

Molecular Weight: 772.82

Molecular Formula: C40H40N10O7

Density: 1.440±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

ZZ-1-31B BPL-201931 ZZ-1-31B

VHL

CDK9
CLK1

Inquiry

Molecular Weight: 997.32

Molecular Formula: C48H68N8O9S3

Density: 1.32±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

8-(4-(4-(3-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)propanoyl)piperazin-1-yl)piperidin-1-yl)-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile BPL-201932 8-(4-(4-(3-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)propanoyl)piperazin-1-yl)piperidin-1-yl)-9-ethyl-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile 2353492-98-3

CRBN

ALK

Inquiry

Molecular Weight: 897.05

Molecular Formula: C50H56N8O8

Density: 1.41±0.1 g/cm3

Description: It is a potent ALK degrader constructed from Alectinib.

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