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E3 Ligase
Target
Molecular Weight
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
FMF-05-178-1 BPL-201893 FMF-05-178-1

VHL

BLK
CSK

Inquiry

Molecular Weight: 1100.28

Molecular Formula: C55H68F3N11O8S

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

FMF-06-098-1 BPL-201894 FMF-06-098-1 2769753-07-1

VHL

AAK1
ABL2
AURKA
AURKB
BUB1B
CDC7
CDK1
CDK12
CDK13
CDK2
CDK4
CDK6
CDK7
CDK9
CHEK1
CSNK1D
EPHA1
FAK
FER
FGFR1
GAK
IRAK4
ITK
LIMK2
MAP4K2
MAP4K3
MAPK6
MAPK7
MARK4
MELK
PKN3
PLK4
PRKAA1
PTK6
RPS6KA4
SIK2
STK35
TNK2
UHMK1
ULK1
Wee1

Inquiry

Molecular Weight: 1073.78

Molecular Formula: C53H69ClN10O8S2

Density: 1.300±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

ImatinIMiD-2 BPL-201895 ImatinIMiD-2

CRBN

ABL1

Inquiry

Molecular Weight: 1020.16

Molecular Formula: C55H61N11O9

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

ImatinIMiD-5 BPL-201896 ImatinIMiD-5 2769851-31-0

CRBN

ABL1

Inquiry

Molecular Weight: 978.12

Molecular Formula: C53H59N11O8

Density: 1.324±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

INY-01-140-1 BPL-201897 INY-01-140-1 2769851-30-9

CRBN

PDK1
PDK2
PDK3

Inquiry

Molecular Weight: 862.94

Molecular Formula: C48H46N8O8

Density: 1.46±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

INY-02-083-01 BPL-201898 INY-02-083-01 2769851-29-6

VHL

AKT1
AKT2
AKT3

Inquiry

Molecular Weight: 1005.30

Molecular Formula: C57H68N10O5S

Density: 1.30±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

INY-02-105 BPL-201899 INY-02-105 2503017-88-5

VHL

AKT1
AKT2
AKT3

Inquiry

Molecular Weight: 956.66

Molecular Formula: C50H66ClN9O6S

Boiling Point: 1126.5±65.0°C at 760 Torr

Density: 1.262±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

INY-02-164 BPL-201900 INY-02-164 2503017-90-9

CRBN

AKT1
AKT2
AKT3
BCKDK
PDK1

Inquiry

Molecular Weight: 857.41

Molecular Formula: C44H53ClN8O8

Boiling Point: 1092.6±65.0°C at 760 Torr

Density: 1.346±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

INY-02-180-01 BPL-201901 INY-02-180-01

VHL

AKT1
AKT2
AKT3

Inquiry

Molecular Weight: 943.14

Molecular Formula: C47H62N10O9S

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

INY-04-026-01 BPL-201902 INY-04-026-01 2769851-28-5

VHL

AKT1
AKT2
AKT3

Inquiry

Molecular Weight: 1014.09

Molecular Formula: C48H59Cl2FN8O7S2

Boiling Point: 1086.6±65.0°C at 760 Torr

Density: 1.38±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

INY-04-125-01 BPL-201903 INY-04-125-01 2769851-27-4

VHL

LATS1
STK17A

Inquiry

Molecular Weight: 975.23

Molecular Formula: C55H62N10O5S

Density: 1.35±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

JWG-118 BPL-201904 JWG-118 2769851-26-3

CRBN

AAK1
AURKA
BMP2K
GAK
Wee1

Inquiry

Molecular Weight: 941.08

Molecular Formula: C46H56N10O10S

Density: 1.356±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

JWG-120 BPL-201905 JWG-120 2769851-25-2

CRBN

AAK1
AURKA

Inquiry

Molecular Weight: 861.98

Molecular Formula: C44H47N9O8S

Density: 1.46±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

JWG-122 BPL-201906 JWG-122 2769850-32-8

VHL

AAK1
GAK

Inquiry

Molecular Weight: 1082.41

Molecular Formula: C55H75N11O8S2

Density: 1.266±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

JWG-123 BPL-201907 JWG-123 2769850-30-6

VHL

AAK1
CDK16
GAK
MARK4
NEK9
RPS6KB1
SIK2
SIK3
SNRK
STK17A
STK17B
Wee1

Inquiry

Molecular Weight: 1050.41

Molecular Formula: C55H75N11O6S2

Density: 1.247±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

JWG-137 BPL-201908 JWG-137 2769850-29-3

VHL

JAK2

Inquiry

Molecular Weight: 1003.31

Molecular Formula: C53H66N10O6S2

Density: 1.33±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

JWG-148 BPL-201909 JWG-148 2769850-28-2

VHL

ABL2
EPHB2
SIK2
TYK2

Inquiry

Molecular Weight: 858.08

Molecular Formula: C47H55N9O5S

Density: 1.272±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

LT2-49 BPL-201910 LT2-49 2769753-30-0

CRBN

AAK1
AURKA
BLK
BMP2K
CDK12
CDK13
CDK17
CDK2
CDK4
CDK5
CDK6
CDK7
CDK9
FER
ITK
LCK
LIMK2
PRKAA1
PTK2B
STK10
Wee1

Inquiry

Molecular Weight: 931.47

Molecular Formula: C44H51ClN10O9S

Density: 1.411±0.06 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

MFH-5-115-2 BPL-201911 MFH-5-115-2 2769850-27-1

CRBN

AURKA
BUB1
BUB1B
CDK4
CSNK1A1
MAP3K1
NUAK1
PIM2
PLK1
RIOK2
STK17A
TTK
UHMK1
Wee1

Inquiry

Molecular Weight: 912.02

Molecular Formula: C45H57N11O10

Density: 1.46±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

MFH-5-126-1 BPL-201912 MFH-5-126-1 2769850-26-0

CRBN

AURKA
BUB1
BUB1B
CDK13
CDK14
CDK17
CDK4
CDK9
CHEK1
CLK1
CSNK1A1
CSNK1D
DAPK1
ERN1
GSK3A
GSK-3beta
MAP3K1
NUAK1
PIK3CG
PIM2
PLK1
RIOK2
STK17A
STK17B
TTK
UHMK1
Wee1

Inquiry

Molecular Weight: 765.70

Molecular Formula: C37H42Cl2N8O6

Boiling Point: 956.1±65.0°C at 760 Torr

Density: 1.45±0.1 g/cm3

Description: It is a multi-targeted degrader, and kinase degradation is dependent on p97.

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