PROTAC Library

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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
PHOTAC-I-1 BPL-201393 PHOTAC-I-1 2370997-92-3

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 907.41

Molecular Formula: C44H43ClN10O8S

Density: 1.52±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-2 BPL-201394 PHOTAC-I-2 2370997-93-4

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 921.44

Molecular Formula: C45H45ClN10O8S

Density: 1.50±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-3 BPL-201395 PHOTAC-I-3 2370997-94-5

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 935.46

Molecular Formula: C46H47ClN10O8S

Density: 1.49±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-4 BPL-201396 PHOTAC-I-4 2370997-95-6

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 949.49

Molecular Formula: C47H49ClN10O8S

Density: 1.47±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-5 BPL-201397 PHOTAC-I-5 2370997-96-7

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 963.52

Molecular Formula: C48H51ClN10O8S

Density: 1.46±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-6 BPL-201398 PHOTAC-I-6 2370997-97-8

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 847.36

Molecular Formula: C42H39ClN10O6S

Density: 1.53±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-7 BPL-201399 PHOTAC-I-7 2370997-98-9

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 875.41

Molecular Formula: C44H43ClN10O6S

Density: 1.50±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-8 BPL-201400 PHOTAC-I-8 2370997-99-0

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 903.47

Molecular Formula: C46H47ClN10O6S

Density: 1.46±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-9 BPL-201401 PHOTAC-I-9 2370998-10-8

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 921.39

Molecular Formula: C44H41ClN10O9S

Density: 1.55±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-10 BPL-201402 PHOTAC-I-10 2370998-05-1

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 909.39

Molecular Formula: C46H37ClN10O7S

Density: 1.55±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-11 BPL-201403 PHOTAC-I-11 2370998-07-3

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 923.41

Molecular Formula: C47H39ClN10O7S

Density: 1.53±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-12 BPL-201404 PHOTAC-I-12 2370998-08-4

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 937.44

Molecular Formula: C48H41ClN10O7S

Density: 1.52±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-I-13 BPL-201405 PHOTAC-I-13 2370998-09-5

CRBN

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 935.42

Molecular Formula: C48H39ClN10O7S

Density: 1.59±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets BET family proteins (BRD2,3,4).

PHOTAC-II-1 BPL-201406 PHOTAC-II-1 2370998-00-6

CRBN

FKBP12

Inquiry

Molecular Weight: 1104.22

Molecular Formula: C58H69N7O15

Density: 1.33±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets FKBP12.

PHOTAC-II-2 BPL-201407 PHOTAC-II-2 2370998-01-7

CRBN

FKBP12

Inquiry

Molecular Weight: 1118.25

Molecular Formula: C59H71N7O15

Density: 1.32±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets FKBP12.

PHOTAC-II-3 BPL-201408 PHOTAC-II-3 2370998-02-8

CRBN

FKBP12

Inquiry

Molecular Weight: 1132.28

Molecular Formula: C60H73N7O15

Density: 1.31±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets FKBP12.

PHOTAC-II-4 BPL-201409 PHOTAC-II-4 2370998-03-9

CRBN

FKBP12

Inquiry

Molecular Weight: 1146.31

Molecular Formula: C61H75N7O15

Density: 1.30±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets FKBP12.

PHOTAC-II-5 BPL-201410 PHOTAC-II-5 2481746-61-4

CRBN

FKBP12

Inquiry

Molecular Weight: 1030.15

Molecular Formula: C55H63N7O13

Density: 1.33±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets FKBP12.

PHOTAC-II-6 BPL-201411 PHOTAC-II-6 2370998-06-2

CRBN

FKBP12

Inquiry

Molecular Weight: 1092.17

Molecular Formula: C59H61N7O14

Density: 1.35±0.1 g/cm3

Description: It is a PHOTAC that optically controls protein degradation and targets FKBP12.

macroPROTAC-1 BPL-201412 macroPROTAC-1 2409844-88-6

VHL

BRD2
BRD3
BRD4

Inquiry

Molecular Weight: 1118.78

Molecular Formula: C54H68ClN9O11S2

Density: 1.42±0.1 g/cm3

Description: It is a macrocyclic PROTAC by adding a cyclizing linker to the BET degrader MZ1. It enhances the degradation potency and selectivity between homologous targets.

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