PROTAC Library

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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
BJG-02-108 BPL-201213 BJG-02-108

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 1157.55

Molecular Formula: C64H100N8O11

Description: It is a tubulin-targeted small molecule degrader.

BJG-02-095 BPL-201214 BJG-02-095

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 1171.53

Molecular Formula: C64H98N8O12

Description: It is a tubulin-targeted small molecule degrader.

BJG-03-088 BPL-201215 BJG-03-088

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 1105.39

Molecular Formula: C58H88N8O13

Description: It is a tubulin-targeted small molecule degrader.

BJG-02-160 BPL-201216 BJG-02-160

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 1149.44

Molecular Formula: C60H92N8O14

Description: It is a tubulin-targeted small molecule degrader.

BJG-02-164 BPL-201217 BJG-02-164

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 1237.54

Molecular Formula: C64H100N8O16

Description: It is a tubulin-targeted small molecule degrader.

BJG-03-089 BPL-201218 BJG-03-089

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 1383.73

Molecular Formula: C71H114N8O19

Description: It is a tubulin-targeted small molecule degrader.

BJG-03-097 BPL-201219 BJG-03-097

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 1143.48

Molecular Formula: C62H94N8O12

Description: It is a tubulin-targeted small molecule degrader.

BJG-03-081 BPL-201220 BJG-03-081

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 703.75

Molecular Formula: C37H41N3O11

Description: It is a tubulin-targeted small molecule degrader.

BJG-03-033-1 BPL-201221 BJG-03-033-1

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 747.80

Molecular Formula: C39H45N3O12

Description: It is a tubulin-targeted small molecule degrader.

BJG-02-158 BPL-201222 BJG-02-158

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 791.85

Molecular Formula: C41H49N3O13

Description: It is a tubulin-targeted small molecule degrader.

BJG-03-033-2 BPL-201223 BJG-03-033-2

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 835.90

Molecular Formula: C43H53N3O14

Description: It is a tubulin-targeted small molecule degrader.

BJG-03-144 BPL-201224 BJG-03-144

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 790.87

Molecular Formula: C41H50N4O12

Description: It is a tubulin-targeted small molecule degrader.

QC-01-175 BPL-201225 QC-01-175 2267290-96-8

CRBN

Tau

Inquiry

Molecular Weight: 626.67

Molecular Formula: C33H34N6O7

Boiling Point: 977.2±65.0°C at 760 Torr

Density: 1.416±0.06 g/cm3

Description: It targets the degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models.

WL40 BPL-201226 WL40 2375283-52-4

CRBN

Rpn13

Inquiry

Molecular Weight: 1019.76

Molecular Formula: C50H47Cl4N5O10

Boiling Point: 1171.6±65.0°C at 760 Torr

Density: 1.444±0.06 g/cm3

Description: It is a covalent ubiquitin receptor Rpn13 degrader in multiple myeloma.

2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-(4-((4-(quinolin-3-ylamino)pyrimidin-2-yl)amino)phenoxy)ethoxy)ethyl)amino)isoindoline-1,3-dione BPL-201227 2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-(4-((4-(quinolin-3-ylamino)pyrimidin-2-yl)amino)phenoxy)ethoxy)ethyl)amino)isoindoline-1,3-dione

CRBN

IGF-1R
Src

Inquiry

Molecular Weight: 672.70

Molecular Formula: C36H32N8O6

Description: It is a proteolysis targeting chimera (PROTAC) for the dual degradation of IGF-1R and Src.

2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-(2-(4-((4-(quinolin-3-ylamino)pyrimidin-2-yl)amino)phenoxy)ethoxy)ethoxy)ethyl)amino)isoindoline-1,3-dione BPL-201228 2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-(2-(4-((4-(quinolin-3-ylamino)pyrimidin-2-yl)amino)phenoxy)ethoxy)ethoxy)ethyl)amino)isoindoline-1,3-dione

CRBN

IGF-1R
Src

Inquiry

Molecular Weight: 716.76

Molecular Formula: C38H36N8O7

Description: It is a proteolysis targeting chimera (PROTAC) for the dual degradation of IGF-1R and Src.

2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-(2-(2-(4-((4-(quinolin-3-ylamino)pyrimidin-2-yl)amino)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)isoindoline-1,3-dione BPL-201229 2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-(2-(2-(4-((4-(quinolin-3-ylamino)pyrimidin-2-yl)amino)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)isoindoline-1,3-dione

CRBN

IGF-1R
Src

Inquiry

Molecular Weight: 760.81

Molecular Formula: C40H40N8O8

Description: It is a proteolysis targeting chimera (PROTAC) for the dual degradation of IGF-1R and Src.

CPR3 BPL-201230 CPR3

CRBN

IGF-1R
Src

Inquiry

Molecular Weight: 625.65

Molecular Formula: C31H31N9O6

Description: It is a proteolysis targeting chimera (PROTAC) for the dual degradation of IGF-1R and Src.

CPR4 BPL-201231 CPR4

CRBN

IGF-1R
Src

Inquiry

Molecular Weight: 669.70

Molecular Formula: C33H35N9O7

Description: It is a proteolysis targeting chimera (PROTAC) for the dual degradation of IGF-1R and Src.

4-((2-(2-(4-((5-Chloro-4-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)amino)phenoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione BPL-201232 4-((2-(2-(4-((5-Chloro-4-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)amino)phenoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

CRBN

IGF-1R
Src

Inquiry

Molecular Weight: 660.09

Molecular Formula: C31H30ClN9O6

Description: It is a proteolysis targeting chimera (PROTAC) for the dual degradation of IGF-1R and Src.

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