2-(2-hydroxyethoxy)ethyl 4-methylbenzenesulfonate

 CAS No.: 118591-58-5  Cat No.: BP-500455 4.5  

Tos-PEG2-OH is a polyethylene glycol (PEG)-based PROTAC linker. Tos-PEG2-OH can be used in the synthesis of a series of PROTACs.

2-(2-hydroxyethoxy)ethyl 4-methylbenzenesulfonate

Structure of 118591-58-5

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Category
PROTAC Linker
Molecular Formula
C₁₁H₁₆O₅S
Molecular Weight
260.31
Appearance
Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Appearance
Liquid
Storage
Pure form, -20°C, 3 years; 4°C, 2 years; In solvent, -80°C, 6 months; -20°C, 1 month
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
2-(2-hydroxyethoxy)ethyl 4-methylbenzenesulfonate
Synonyms
Ethanol, 2-(2-hydroxyethoxy)-, 1-(4-Methylbenzenesulfonate); Tos-PEG2-Alcohol
Boiling Point
427.4±30.0 °C at 760 mmHg
Density
1.3±0.1 g/cm3
InChI Key
KLDLLRZCWYKJBD-UHFFFAOYSA-N
InChI
InChI=1S/C11H16O5S/c1-10-2-4-11(5-3-10)17(13,14)16-9-8-15-7-6-12/h2-5,12H,6-9H2,1H3
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)OCCOCCO

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It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: BI-4464 | ARV-825 | NH-bis(PEG3-acid) | endo-BCN-PEG2-alcohol | N-(m-PEG4)-N'-(azide-PEG4)-Cy7 | Azido-PEG6-t-butyl ester | Bis-PEG10-NHS ester | Propargyl-PEG11-methane | Propargyl-PEG3-t-butyl ester | Azide-PEG3-Sulfone-PEG3-azide | 2-(2-hydroxyethoxy)ethyl 4-methylbenzenesulfonate

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