Azido-PEG4-amine

Name: Azido-PEG4-amine
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 951671-92-4

Cat No.: BP-500025

Purity: ≥95% 4.5

N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Structure of 951671-92-4

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Category

PROTAC Linker

Molecular Formula

C10H22N4O4

Molecular Weight

262.31

Appearance

Colorless to Light Yellow to Light Orange Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity

≥95%

Solubility

Soluble in DCM, DMF, DMSO, Water

Appearance

Colorless to Light Yellow to Light Orange Liquid

Storage

Store at 2-8°C

Shipping

Room temperature in continental US; may vary elsewhere

IUPACName

2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanamine

Synonyms

14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane

Density

1.10 g/mL

InChI Key

ZMBGKXBIVYXREN-UHFFFAOYSA-N

InChI

InChI=1S/C10H22N4O4/c11-1-3-15-5-7-17-9-10-18-8-6-16-4-2-13-14-12/h1-11H2

Canonical SMILES

C(COCCOCCOCCOCCN=[N+]=[N-])N

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C₁V₁ = C₂V₂