Bis-PEG17-NHS ester

 CAS No.: 2221948-93-0  Cat No.: BP-500972  Purity: >98.0% 4.5  

Bis-PEG17-NHS ester is a long-chain bifunctional PEG linker with dual NHS esters for efficient amine coupling in ADCs. It enhances hydrophilicity and steric spacing between antibody and payload, improving pharmacokinetics and reducing immunogenicity in targeted drug delivery.

Bis-PEG17-NHS ester

Structure of 2221948-93-0

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Category
PROTAC Linker
Molecular Formula
C46H80N2O25
Molecular Weight
1061.13
Appearance
Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
10 mm in DMSO
Appearance
Solid
ShelfLife
-20°C 3 years powder; -80°C 2 years in solvent
Storage
-20°C
Shipping
Room temperature
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonyms
NHS-PEG16-NHS
InChI Key
NKGAYEIPIYDEJM-UHFFFAOYSA-N
InChI
InChI=1S/C46H80N2O25/c49-41-1-2-42(50)47(41)72-45(53)5-7-55-9-11-57-13-15-59-17-19-61-21-23-63-25-27-65-29-31-67-33-35-69-37-39-71-40-38-70-36-34-68-32-30-66-28-26-64-24-22-62-20-18-60-16-14-58-12-10-56-8-6-46(54)73-48-43(51)3-4-44(48)52/h1-40H2
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: Bis-PEG17-NHS ester

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