m-PEG5-COOH

 CAS No.: 81836-43-3  Cat No.: BP-500572  Purity: ≥95% 4.5  

m-PEG5-COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

m-PEG5-COOH

Structure of 81836-43-3

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Category
PROTAC Linker
Molecular Formula
C12H24O7
Molecular Weight
280.31
Appearance
Pale Yellow or Colorless Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMF, DMSO, Water
Appearance
Pale Yellow or Colorless Oily Liquid
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
3-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
mPEG4-propionic acid; 2,5,8,11,14-Pentaoxaheptadecan-17-oic acid; mPEG4-OC2H4COOH; m-PEG5-acid; mPEG4-CH2CH2COOH; 4,7,10,13,16-Pentaoxaheptadecanoic acid; 2,5,8,11,14-Pentaoxa-17-heptadecanoic Acid; MeO-(CH2CH2O)4-CH2CH2COOH
Boiling Point
393.0±37.0 °C at 760 mmHg
Density
1.107±0.06 g/cm3 (Predicted)
InChI Key
KTTNUZHOERZAMX-UHFFFAOYSA-N
InChI
InChI=1S/C12H24O7/c1-15-4-5-17-8-9-19-11-10-18-7-6-16-3-2-12(13)14/h2-11H2,1H3,(H,13,14)
Canonical SMILES
COCCOCCOCCOCCOCCC(=O)O

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: DBCO-PEG1-acid | COOH-PEG6-COOtBu | Azido-PEG2-hydrazide-Boc | Benzyl-PEG5-MS | Amino-PEG5-propionic acid | Amino-PEG7-propionic acid | Azido-PEG5-Boc | Tos-PEG1-CH2-Boc | Ald-CH2-PEG3-azide | Azido-PEG8-amine | m-PEG5-COOH

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