Pomalidomide-C2-COOH

 CAS No.: 2225940-46-3  Cat No.: BP-100157  Purity: ≥95% 4.5  

Pomalidomide-C2-COOH is a Pomalidomide-based cereblon ligand with a linker, which is a useful precursor for the synthesis of PROTAC degraders.

Pomalidomide-C2-COOH

Structure of 2225940-46-3

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C16H15N3O6
Molecular Weight
345.31

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
IUPACName
3-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]propanoic acid
Synonyms
Pomalidomide-C2-acid; 3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propanoic acid; 3-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}propanoic acid; β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-; N-[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-β-alanine; Thalidomide-NH-C2-COOH
Boiling Point
708.5±60.0°C (Predicted)
Density
1.578±0.06 g/cm3 (Predicted)
InChI Key
HIZAHNGGMCSUEV-UHFFFAOYSA-N
InChI
InChI=1S/C16H15N3O6/c20-11-5-4-10(14(23)18-11)19-15(24)8-2-1-3-9(13(8)16(19)25)17-7-6-12(21)22/h1-3,10,17H,4-7H2,(H,21,22)(H,18,20,23)
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCC(=O)O

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

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