Propargyl-PEG2-acid

 CAS No.: 1859379-85-3  Cat No.: BP-500184  Purity: ≥98.0% 4.5  

Propargyl-PEG2-acid is an alkyne-functionalized PEG linker with a carboxylic acid group, supporting copper-free click chemistry in ADC construction. Its PEG2 spacer offers hydrophilicity and facilitates site-specific payload conjugation for enhanced therapeutic efficacy.

Propargyl-PEG2-acid

Structure of 1859379-85-3

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
PROTAC Linker
Molecular Formula
C8H12O4
Molecular Weight
172.18
Appearance
Pale Yellow Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

SizePriceStockQuantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

  • mg to g scale for early stage;
  • CDMO and CMO support.
  • 24/7 customer service;
  • 100% quality assurance;
  • Efficient global delivery;
  • Over 95% customer satisfaction.
Popular Publications Citing BOC Sciences Products
Purity
≥98.0%
Solubility
Soluble in DMSO
Appearance
Pale Yellow Oily Matter
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Shipping
Room temperature, or blue ice upon request.
IUPACName
3-(2-prop-2-ynoxyethoxy)propanoic acid
Synonyms
Propyne-PEG1-CH2CH2COOH; 3-(2-(Prop-2-yn-1-yloxy)ethoxy)propanoic acid; 3-[2-(2-Propyn-1-yloxy)ethoxy]propanoic acid; Propargyl-PEG1-COOH; Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-
Boiling Point
306.6±27.0°C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
NNWHATPXNWOQKD-UHFFFAOYSA-N
InChI
InChI=1S/C8H12O4/c1-2-4-11-6-7-12-5-3-8(9)10/h1H,3-7H2,(H,9,10)
Canonical SMILES
C#CCOCCOCCC(=O)O
Biological Activity
Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]
ConcentrationVolumeMass1 mg5 mg10 mg
1 mM5.8079 mL29.0394 mL58.0788 mL
5 mM1.1616 mL5.8079 mL11.6158 mL
10 mM0.5808 mL2.9039 mL5.8079 mL

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

Calculate
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: Aminooxy-PEG3-Aminooxy | Aminooxy-PEG3-NHBoc | DBCO-PEG5-acid | Amino-PEG12-Tris(-PEG24-acid)3 | Propargyl-PEG3-phosphonic acid | HS-PEG24-CH2CH2COOH | Bis-propargyl-PEG12 | Propargyl-PEG2-acid

Related Product Recommendations

In Stock Purity: >95% Hot
Triethylene Glycol Mono(2-propynyl) Ether
Triethylene Glycol Mono(2-propynyl) Ether

CAS: 208827-90-1
In Stock Purity: ≥95% Hot
Propargyl-PEG5-acid
Propargyl-PEG5-acid

CAS: 1245823-51-1
In Stock Purity: ≥98% Hot
Protein degrader 1 hydrochloride
Protein degrader 1 hydrochloride

CAS: 1448189-80-7
In Stock Purity: >95% Hot
DBCO-PEG4-NHS ester
DBCO-PEG4-NHS ester

CAS: 1427004-19-0
In Stock Purity: ≥ 98% Hot
Ursolic acid
Ursolic acid

CAS: 77-52-1
In Stock Purity: 97% Hot
Pomalidomide
Pomalidomide

CAS: 19171-19-8
BOC Sciences Support

Please contact us with any specific requirements and we will get back to you as soon as possible.


  • Verification code

We invite you to contact us at or through our contact form above for more information about our services and products.

USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
Germany
Copyright © 2025 BOC Sciences. All Rights Reserved.
Inquiry Basket
Loading......
Delete selected Go to checkout