Propargyl-PEG5-NHS ester

 CAS No.: 1393330-40-9  Cat No.: BP-501458  Purity: >98.0% 4.5  

Propargyl-PEG5-NHS ester is an extended PEG linker with NHS ester and terminal alkyne, designed for CuAAC-based ADC conjugation. The PEG5 chain improves solubility and reduces steric hindrance, ideal for constructing stable, high-performance antibody-drug conjugates.

Propargyl-PEG5-NHS ester

Structure of 1393330-40-9

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Category
PROTAC Linker
Molecular Formula
C18H27NO9
Molecular Weight
401.41
Appearance
Light yellow to brown clear liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
10 mm in DMSO
Appearance
Light yellow to brown clear liquid
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at 4 °C
Shipping
Room temperature
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]propanoate
Synonyms
Alkyne-PEG5-NHS;Alkyne-PEG5-N-hydroxysuccinimidyl ester; 2,5-Dioxopyrrolidin-1-yl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
Boiling Point
497.6±55.0 °C at 760 mmHg
Density
1.2±0.1 g/cm3
InChI Key
ACZDUKRWTPZVRP-UHFFFAOYSA-N
InChI
InChI=1S/C18H27NO9/c1-2-6-23-8-10-25-12-14-27-15-13-26-11-9-24-7-5-18(22)28-19-16(20)3-4-17(19)21/h1H,3-15H2
Canonical SMILES
C#CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Tetrakis-(N-succinimidylcarboxypropyl)pentaerythritol | Fmoc-N-amido-PEG1-acid | m-PEG5-2-methylacrylate | Azido-PEG8-THP | Amino-PEG10-CH2-Boc | TAMRA-PEG3-Azide | mPEG3-acetic acid | Methyltetrazine-PEG6-maleimide | m-PEG49-NHS ester | Acid-PEG4-mono-methyl ester | Propargyl-PEG5-NHS ester

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