t-Boc-N-amido-PEG1-propionic acid

 CAS No.: 1260092-44-1  Cat No.: BP-500804  Purity: ≥95% 4.5  

t-Boc-N-amido-PEG1-propionic acid is a cleavable (1-unit PEG) ADC linker, as well as a PEG- and alkyl/ether-based PROTAC linker that can be used to synthesize antibody-drug conjugates (ADCs) or PROTACs.

t-Boc-N-amido-PEG1-propionic acid

Structure of 1260092-44-1

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Category
PROTAC Linker
Molecular Formula
C10H19NO5
Molecular Weight
233.26
Appearance
Pale Yellow or Colorless Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO
Appearance
Pale Yellow or Colorless Oily Liquid
Storage
Store at 2-8°C
Shipping
Room temperature
IUPACName
3-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]propanoic acid
Synonyms
t-Boc-N-amido-PEG1-acid; Boc-NH-PEG1-CH2CH2COOH; t-Boc-NH-amido-PEG1-COOH; Boc-NH-PEG1-COOH; 3-[2-(Boc-amino)ethoxy]propanoic Acid; 3-(2-N-Boc-aminoethoxy)propanoic acid; 3-(2-((tert-Butoxycarbonyl)amino)ethoxy)propanoic acid; Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-; 3-[2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)ethoxy]propanoic acid
Boiling Point
385.0±27.0 °C at 760 mmHg
Density
1.127±0.06 g/cm3 (Predicted)
InChI Key
YGNSGMAPLOVGIU-UHFFFAOYSA-N
InChI
InChI=1S/C10H19NO5/c1-10(2,3)16-9(14)11-5-7-15-6-4-8(12)13/h4-7H2,1-3H3,(H,11,14)(H,12,13)
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCC(=O)O

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Amino-PEG5-t-butyl ester | Methylamino-PEG1-acid | Boc-Aminooxy-PEG3-acid | t-Boc-N-amido-PEG3-azide | t-Boc-N-amido-PEG1-propionic acid

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