Acs-PEG4-propargyl

 CAS No.: 1422540-88-2  Cat No.: BP-500565  Purity: ≥95% 4.5  

Acs-PEG4-propargyl is a PEG linker containing a sulfur acetyl group and a propargyl moiety. The sulfur acetyl group can be deprotected to produce a thiol compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of the compounds in the aqueous media.

Acs-PEG4-propargyl

Structure of 1422540-88-2

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PROTAC Linker
Molecular Formula
C13H22O5S
Molecular Weight
290.37
Appearance
Yellow to Amber to Dark Red Clear Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMF, DMSO
Appearance
Yellow to Amber to Dark Red Clear Liquid
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
S-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethyl] ethanethioate
Synonyms
S-acetyl-PEG4-Propargyl; Acetylthio-PEG4-Alkyne; S-acetyl-PEG4-alkyne; S-(3,6,9,12-Tetraoxapentadec-14-yn-1-yl) ethanethioate; Ethanethioic acid, S-3,6,9,12-tetraoxapentadec-14-yn-1-yl ester
Boiling Point
375.6±37.0°C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
IOVXBDYSVBLUMS-UHFFFAOYSA-N
InChI
InChI=1S/C13H22O5S/c1-3-4-15-5-6-16-7-8-17-9-10-18-11-12-19-13(2)14/h1H,4-12H2,2H3
Canonical SMILES
CC(=O)SCCOCCOCCOCCOCC#C

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It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Ald-CH2-PEG3-azide | Azido-PEG8-amine | m-PEG5-COOH | Azido-PEG3-aldehyde | Biotin-PEG2-NH-Mal | Benzyl-PEG8-MS | Propargyl-PEG4-thiol | Propargyl-PEG8-acid | Bis-PEG2-t-butyl ester | Aminooxy-PEG3-bromide | Acs-PEG4-propargyl

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