Br-PEG1-acid

 CAS No.: 1393330-33-0  Cat No.: BP-501564  Purity: ≥95% 4.5  

Br-PEG1-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Br-PEG1-acid

Structure of 1393330-33-0

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Category
PROTAC Linker
Molecular Formula
C5H9BrO3
Molecular Weight
197.03
Appearance
Pale Yellow Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Appearance
Pale Yellow Oily Matter
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
3-(2-bromoethoxy)propanoic acid
Synonyms
Bromo-PEG1-Acid; Bromo-PEG1-propionic acid; Br-PEG1-CH2CH2COOH; Propanoic acid, 3-(2-bromoethoxy)-
Boiling Point
301.7±22.0°C at 760 mmHg
Density
1.6±0.1 g/cm3
InChI Key
REBYHCQUFPLTTH-UHFFFAOYSA-N
InChI
InChI=1S/C5H9BrO3/c6-2-4-9-3-1-5(7)8/h1-4H2,(H,7,8)
Canonical SMILES
C(COCCBr)C(=O)O

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It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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