m-PEG8-Ms

 CAS No.: 1059588-19-0  Cat No.: BP-500858  Purity: ≥95% 4.5  

m-PEG8-Ms is a mesylate-activated PEG linker used in antibody-drug conjugates for efficient nucleophilic substitution reactions. Its PEG8 spacer increases hydrophilicity and solubility of payloads, improving bioconjugate stability and pharmacokinetic profiles in targeted therapies.

m-PEG8-Ms

Structure of 1059588-19-0

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Category
PROTAC Linker
Molecular Formula
C18H38O11S
Molecular Weight
462.55

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
10 mm in DMSO
ShelfLife
-20°C 3 years powder; -80°C 2 years in solvent
Storage
-20°C
Shipping
Room temperature
IUPACName
2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl methanesulfonate
Synonyms
2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl methanesulfonate
InChI Key
AQFJPOUIRSKMIV-UHFFFAOYSA-N
InChI
InChI=1S/C18H38O11S/c1-21-3-4-22-5-6-23-7-8-24-9-10-25-11-12-26-13-14-27-15-16-28-17-18-29-30(2,19)20/h3-18H2,1-2H3
Canonical SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)C

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: m-PEG2-Ms | Hydroxy-PEG1-methyl ester | HO-PEG5-OH | Hydroxy-PEG8-propionic acid | mPEG5-amine | 4,7,10,13,16,19,22,25,28,31,34-Undecaoxaheptatriaconta-1,36-diyne | Bromo-PEG4-MS | Mal-PEG1-acid | Propargyl-PEG2-Ms | Thiol-PEG3-Boc | m-PEG8-Ms

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