Pomalidomide-C4-COOH

 CAS No.: 2225940-48-5  Cat No.: BP-100158  Purity: ≥95% 4.5  

Pomalidomide-C4-COOH is a synthetic E3 ligase ligand-linker conjugate that incorporates Pomalidomide-based CRBN ligands and linkers used in PROTAC technology.

Pomalidomide-C4-COOH

Structure of 2225940-48-5

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C18H19N3O6
Molecular Weight
373.36
Appearance
Yellow Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMF, DMSO
Appearance
Yellow Solid
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
IUPACName
5-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]pentanoic acid
Synonyms
Pomalidomide-C4-acid; Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-; 5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)pentanoic acid; 5-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]pentanoic acid; 5-{[2-(2,6-Dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}pentanoic acid; Pomalidomide 4'-alkylC4-acid; JUN 40485; JUN-40485; Thalidomide-NH-C4-COOH
Boiling Point
712.2±60.0°C at 760 mmHg
Density
1.5±0.1 g/cm3
InChI Key
JUPYDAIBDNUUIF-UHFFFAOYSA-N
InChI
InChI=1S/C18H19N3O6/c22-13-8-7-12(16(25)20-13)21-17(26)10-4-3-5-11(15(10)18(21)27)19-9-2-1-6-14(23)24/h3-5,12,19H,1-2,6-9H2,(H,23,24)(H,20,22,25)
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCC(=O)O

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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