Propargyl-PEG6-acid

 CAS No.: 1951438-84-8  Cat No.: BP-500192  Purity: >98.0% 4.5  

Propargyl-PEG6-acid is a hydrophilic linker with an alkyne group for click chemistry and a carboxylic acid for conjugation. Used in ADC linker development to improve payload accessibility and aqueous solubility in therapeutic antibody conjugates.

Propargyl-PEG6-acid

Structure of 1951438-84-8

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Category
PROTAC Linker
Molecular Formula
C16H28O8
Molecular Weight
348.39
Appearance
Pale Yellow or Colorless Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
Soluble in DMSO, Water
Appearance
Pale Yellow or Colorless Oily Liquid
ShelfLife
≥ 2 years
Storage
Store at 2-8°C
Shipping
Room temperature
IUPACName
3-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
Propyne-PEG5-CH2CH2COOH; Alkyne-PEG6-COOH; Propargyl-PEG6-COOH; Propargyl-PEG5-CH2CH2COOH; 4,7,10,13,16,19-Hexaoxadocos-21-yn-1-oic acid; 4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid
Boiling Point
462.8±45.0 °C at 760 mmHg
Density
1.126±0.06 g/cm3 (Predicted)
InChI Key
XRSJYQQOJNYUDV-UHFFFAOYSA-N
InChI
InChI=1S/C16H28O8/c1-2-4-19-6-8-21-10-12-23-14-15-24-13-11-22-9-7-20-5-3-16(17)18/h1H,3-15H2,(H,17,18)
Canonical SMILES
C#CCOCCOCCOCCOCCOCCOCCC(=O)O

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