| Structure |
Catalog |
Product Name |
CAS |
E3 Ligase |
Target |
Inquiry |
![(2R,4S)-1-((S)-18-(tert-Butyl)-1-(2-(5-(6-(5-((2,4-difluorophenyl)sulfonamido)-6-methoxypyridin-3-yl)imidazo[1,2-a]pyridin-3-yl)-1,3,4-oxadiazol-2-yl)phenyl)-1,16-dioxo-5,8,11,14-tetraoxa-2,17-diazanonadecan-19-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide](https://resource.bocsci.com/structure/2766352-80-9.gif) |
BPL-202453 |
(2R,4S)-1-((S)-18-(tert-Butyl)-1-(2-(5-(6-(5-((2,4-difluorophenyl)sulfonamido)-6-methoxypyridin-3-yl)imidazo[1,2-a]pyridin-3-yl)-1,3,4-oxadiazol-2-yl)phenyl)-1,16-dioxo-5,8,11,14-tetraoxa-2,17-diazanonadecan-19-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
2766352-80-9 |
VHL |
PI3Kalpha |
Inquiry |
|
Molecular Weight: 1250.37
Molecular Formula: C60H65F2N11O13S2
Density: 1.44±0.1 g/cm3
Description: It is a VHL-based PROTAC that targets the degradation of PI3K kinase.
|
![(2R,4S)-1-((S)-21-(tert-Butyl)-1-(2-(5-(6-(5-((2,4-difluorophenyl)sulfonamido)-6-methoxypyridin-3-yl)imidazo[1,2-a]pyridin-3-yl)-1,3,4-oxadiazol-2-yl)phenyl)-1,19-dioxo-5,8,11,14,17-pentaoxa-2,20-diazadocosan-22-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide](https://resource.bocsci.com/structure/2766352-81-0.gif) |
BPL-202454 |
(2R,4S)-1-((S)-21-(tert-Butyl)-1-(2-(5-(6-(5-((2,4-difluorophenyl)sulfonamido)-6-methoxypyridin-3-yl)imidazo[1,2-a]pyridin-3-yl)-1,3,4-oxadiazol-2-yl)phenyl)-1,19-dioxo-5,8,11,14,17-pentaoxa-2,20-diazadocosan-22-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
2766352-81-0 |
VHL |
PI3Kalpha |
Inquiry |
|
Molecular Weight: 1294.43
Molecular Formula: C62H69F2N11O14S2
Density: 1.42±0.1 g/cm3
Description: It is a VHL-based PROTAC that targets the degradation of PI3K kinase.
|
![(2R,4S)-1-((S)-24-(tert-Butyl)-1-(2-(5-(6-(5-((2,4-difluorophenyl)sulfonamido)-6-methoxypyridin-3-yl)imidazo[1,2-a]pyridin-3-yl)-1,3,4-oxadiazol-2-yl)phenyl)-1,22-dioxo-5,8,11,14,17,20-hexaoxa-2,23-diazapentacosan-25-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide](https://resource.bocsci.com/structure/2766352-82-1.gif) |
BPL-202455 |
(2R,4S)-1-((S)-24-(tert-Butyl)-1-(2-(5-(6-(5-((2,4-difluorophenyl)sulfonamido)-6-methoxypyridin-3-yl)imidazo[1,2-a]pyridin-3-yl)-1,3,4-oxadiazol-2-yl)phenyl)-1,22-dioxo-5,8,11,14,17,20-hexaoxa-2,23-diazapentacosan-25-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
2766352-82-1 |
VHL |
PI3Kalpha |
Inquiry |
|
Molecular Weight: 1338.48
Molecular Formula: C64H73F2N11O15S2
Density: 1.41±0.1 g/cm3
Description: It is a VHL-based PROTAC that targets the degradation of PI3K kinase.
|
![3-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide](https://resource.bocsci.com/structure/protac2928.gif) |
BPL-202456 |
3-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 785.83
Molecular Formula: C39H39N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![4-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)butanamide](https://resource.bocsci.com/structure/protac2929.gif) |
BPL-202457 |
4-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)butanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 799.85
Molecular Formula: C40H41N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![5-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentanamide](https://resource.bocsci.com/structure/protac2930.gif) |
BPL-202458 |
5-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 813.88
Molecular Formula: C41H43N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![6-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)hexanamide](https://resource.bocsci.com/structure/protac2931.gif) |
BPL-202459 |
6-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)hexanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 827.91
Molecular Formula: C42H45N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![2-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)acetamide](https://resource.bocsci.com/structure/protac2932.gif) |
BPL-202460 |
2-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)acetamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 771.80
Molecular Formula: C38H37N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![2-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide](https://resource.bocsci.com/structure/protac2933.gif) |
BPL-202461 |
2-(4-((4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 785.83
Molecular Formula: C39H39N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![3-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide](https://resource.bocsci.com/structure/protac2934.gif) |
BPL-202462 |
3-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 813.88
Molecular Formula: C41H43N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![4-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)butanamide](https://resource.bocsci.com/structure/protac2935.gif) |
BPL-202463 |
4-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)butanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 827.91
Molecular Formula: C42H45N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![5-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentanamide](https://resource.bocsci.com/structure/protac2936.gif) |
BPL-202464 |
5-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 841.93
Molecular Formula: C43H47N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![6-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)hexanamide](https://resource.bocsci.com/structure/protac2937.gif) |
BPL-202465 |
6-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)hexanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 855.96
Molecular Formula: C44H49N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![2-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)acetamide](https://resource.bocsci.com/structure/protac2938.gif) |
BPL-202466 |
2-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)acetamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 799.85
Molecular Formula: C40H41N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![2-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide](https://resource.bocsci.com/structure/protac2939.gif) |
BPL-202467 |
2-(4-(3-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 813.88
Molecular Formula: C41H43N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![3-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide](https://resource.bocsci.com/structure/protac2940.gif) |
BPL-202468 |
3-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 827.91
Molecular Formula: C42H45N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![4-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)butanamide](https://resource.bocsci.com/structure/protac2941.gif) |
BPL-202469 |
4-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)butanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 841.93
Molecular Formula: C43H47N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![5-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentanamide](https://resource.bocsci.com/structure/protac2942.gif) |
BPL-202470 |
5-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 855.96
Molecular Formula: C44H49N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![6-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)hexanamide](https://resource.bocsci.com/structure/protac2943.gif) |
BPL-202471 |
6-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)hexanamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 869.99
Molecular Formula: C45H51N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
![2-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)acetamide](https://resource.bocsci.com/structure/protac2944.gif) |
BPL-202472 |
2-(4-(4-(4-Amino-5-(4-(3-(5-(tert-butyl)isoxazol-3-yl)ureido)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)butyl)-1H-1,2,3-triazol-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)acetamide |
|
CRBN |
FLT3
FLT3-ITD
FLT3-ITD-D835V
FLT3-ITD-F691L |
Inquiry |
|
Molecular Weight: 813.88
Molecular Formula: C41H43N13O6
Description: It is a proteolysis targeting chimera (PROTAC) that degrades FLT3-ITD protein.
|
