PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-202293	N-(6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)-6-methyl-7-oxo-4-(2-phenoxyphenyl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2585561-30-2	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 714.78 Molecular Formula: C40H38N6O7 Boiling Point: 965.4±65.0°C at 760 Torr Density: 1.381±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202294	N-(5-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-5-oxopentyl)-6-methyl-7-oxo-4-(2-phenoxyphenyl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2585561-31-3	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 785.86 Molecular Formula: C43H43N7O8 Boiling Point: 1068.7±65.0°C at 760 Torr Density: 1.372±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202295	N-(6-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-6-oxohexyl)-6-methyl-7-oxo-4-(2-phenoxyphenyl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2585561-32-4	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 799.89 Molecular Formula: C44H45N7O8 Boiling Point: 1070.8±65.0°C at 760 Torr Density: 1.357±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202296	N-(7-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-7-oxoheptyl)-6-methyl-7-oxo-4-(2-phenoxyphenyl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2585561-33-5	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 813.91 Molecular Formula: C45H47N7O8 Boiling Point: 1073.3±65.0°C at 760 Torr Density: 1.343±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202297	N-(4-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-6-methyl-7-oxo-4-(2-phenoxyphenyl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2585561-36-8	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 819.88 Molecular Formula: C46H41N7O8 Boiling Point: 1091.2±65.0°C at 760 Torr Density: 1.400±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202298	N-(4-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-6-methyl-7-oxo-4-phenyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2767532-67-0	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 727.78 Molecular Formula: C40H37N7O7 Boiling Point: 1057.5±65.0°C at 760 Torr Density: 1.414±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202299	N-(4-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-4-(3-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2767532-69-2	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 785.86 Molecular Formula: C43H43N7O8 Boiling Point: 1093.8±65.0°C at 760 Torr Density: 1.397±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202300	N-(4-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-4-(2-isopropoxyphenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2767532-70-5	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 785.86 Molecular Formula: C43H43N7O8 Boiling Point: 1075.9±65.0°C at 760 Torr Density: 1.373±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202301	4-(2-Cyclopropoxyphenyl)-N-(4-((4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2767532-71-6	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 783.84 Molecular Formula: C43H41N7O8 Boiling Point: 1096.8±65.0°C at 760 Torr Density: 1.430±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202302	N-(4-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-4-(2-isopropoxy-5-(prop-1-en-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2767532-72-7	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 825.92 Molecular Formula: C46H47N7O8 Boiling Point: 1103.2±65.0°C at 760 Torr Density: 1.336±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202303	N-(4-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-6-methyl-7-oxo-4-(2-phenoxy-5-(prop-1-en-2-yl)phenyl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2767532-73-8	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 859.94 Molecular Formula: C49H45N7O8 Boiling Point: 1109.4±65.0°C at 760 Torr Density: 1.362±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202304	N-(4-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-4-(5-(2-hydroxypropan-2-yl)-2-isopropoxyphenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2585561-47-1	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 843.94 Molecular Formula: C46H49N7O9 Boiling Point: 1115.8±65.0°C at 760 Torr Density: 1.361±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202305	4-(2-Cyclopropoxy-5-(2-hydroxypropan-2-yl)phenyl)-N-(4-((4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2585561-48-2	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 841.92 Molecular Formula: C46H47N7O9 Boiling Point: 1135.3±65.0°C at 760 Torr Density: 1.413±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202306	N-(4-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)carbamoyl)benzyl)-4-(5-(2-hydroxypropan-2-yl)-2-phenoxyphenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2585561-49-3	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 877.96 Molecular Formula: C49H47N7O9 Boiling Point: 1126.1±65.0°C at 760 Torr Density: 1.387±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.
	BPL-202307	2-(2-(4-(3,4-Dichlorophenyl)-5-(2-((4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)amino)-2-oxoethyl)thiazol-2-yl)hydrazineylidene)-3-(2-nitrophenyl)propanoic acid	2769744-04-7	CRBN	eIF4E	Inquiry
Molecular Weight: 893.72 Molecular Formula: C39H34Cl2N8O11S Density: 1.62±0.1 g/cm3 Description: It is a cell-permeable PROTAC-degrader capable of binding eIF4E and successfully engaging Cereblon, which targets proteins for proteolysis.
	BPL-202308	2-(2-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)hydrazineylidene)-N-(4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)propanamide	2769744-16-1	CRBN	eIF4E	Inquiry
Molecular Weight: 663.76 Molecular Formula: C35H33N7O5S Density: 1.43±0.1 g/cm3 Description: It is a cell-permeable PROTAC-degrader capable of binding eIF4E and successfully engaging Cereblon, which targets proteins for proteolysis.
	BPL-202309	2-(2-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)hydrazineylidene)-N-(4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)-3-(2-nitrophenyl)propanamide	2769744-20-7	CRBN	eIF4E	Inquiry
Molecular Weight: 784.86 Molecular Formula: C41H36N8O7S Density: 1.46±0.1 g/cm3 Description: It is a cell-permeable PROTAC-degrader capable of binding eIF4E and successfully engaging Cereblon, which targets proteins for proteolysis.
	BPL-202310	2-(2-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)hydrazineylidene)-N-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)propanamide	2769744-37-6	CRBN	eIF4E	Inquiry
Molecular Weight: 635.71 Molecular Formula: C33H29N7O5S Density: 1.47±0.1 g/cm3 Description: It is a cell-permeable PROTAC-degrader capable of binding eIF4E and successfully engaging Cereblon, which targets proteins for proteolysis.
	BPL-202311	2-(2-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)hydrazineylidene)-N-(3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propyl)propanamide	2769744-33-2	CRBN	eIF4E	Inquiry
Molecular Weight: 649.73 Molecular Formula: C34H31N7O5S Density: 1.45±0.1 g/cm3 Description: It is a cell-permeable PROTAC-degrader capable of binding eIF4E and successfully engaging Cereblon, which targets proteins for proteolysis.
	BPL-202312	((2-(2-(4-(3,4-Dichlorophenyl)-5-(2-((2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)amino)-2-oxoethyl)thiazol-2-yl)hydrazineylidene)propanoyl)oxy)methyl pivalate	2769744-25-2	CRBN	eIF4E	Inquiry
Molecular Weight: 800.68 Molecular Formula: C35H35Cl2N7O9S Density: 1.54±0.1 g/cm3 Description: It is a cell-permeable PROTAC-degrader capable of binding eIF4E and successfully engaging Cereblon, which targets proteins for proteolysis.