Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-202273	(2S,4R)-1-((S)-2-(8-(((E)-4-((2-((2-(Dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)amino)-4-oxobut-2-en-1-yl)(methyl)amino)octanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-13-3	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1097.44 Molecular Formula: C60H80N12O6S Density: 1.23±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202274	(2S,4R)-1-((S)-2-(10-(((E)-4-((2-((2-(Dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)amino)-4-oxobut-2-en-1-yl)(methyl)amino)decanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-14-4	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1125.48 Molecular Formula: C62H84N12O6S Density: 1.22±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202275	(2S,4R)-1-((S)-2-(7-((2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)(2-(dimethylamino)ethyl)amino)heptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-15-5	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1026.32 Molecular Formula: C56H71N11O6S Density: 1.26±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202276	(2S,4R)-1-((S)-5-(2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-23-(tert-butyl)-2-methyl-12,21-dioxo-16,19-dioxa-2,5,13,22-tetraazatetracosan-24-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-16-6	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1171.48 Molecular Formula: C62H82N12O9S Density: 1.27±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202277	(2S,4R)-1-((S)-5-(2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-22-(tert-butyl)-2-methyl-12,20-dioxo-2,5,13,21-tetraazatricosan-23-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-17-7	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1153.51 Molecular Formula: C63H84N12O7S Density: 1.24±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202278	(2S,4R)-1-((S)-2-(8-((2-((2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)(methyl)amino)ethyl)(methyl)amino)octanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-18-8	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1040.35 Molecular Formula: C57H73N11O6S Density: 1.25±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202279	(2S,4R)-1-((S)-2-(2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-18-(tert-butyl)-5-methyl-7,16-dioxo-11,14-dioxa-2,5,8,17-tetraazanonadecan-19-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-19-9	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1101.34 Molecular Formula: C57H72N12O9S Density: 1.30±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202280	(2S,4R)-1-((S)-2-(7-(2-(4-(2-(2-Cyano-3-cyclopropylacrylamido)-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)acetamido)heptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-20-2	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1146.43 Molecular Formula: C62H75N13O7S Density: 1.34±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202281	(2S,4R)-1-((S)-2-(7-(2-(4-(2-(2-Cyano-3-(pyridin-4-yl)acrylamido)-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)acetamido)heptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-21-3	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1183.45 Molecular Formula: C64H74N14O7S Density: 1.33±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202282	N1-(4-Cyano-5-((4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-(4-methylpiperazin-1-yl)phenyl)amino)-2-methyl-5-oxopent-3-en-2-yl)-N7-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)heptanediamide	2768472-22-4	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1134.42 Molecular Formula: C61H75N13O7S Density: 1.30±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202283	N1-(4-Cyano-5-((2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)amino)-2-methyl-5-oxopent-3-en-2-yl)-N8-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)octanediamide	2768472-23-5	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1150.46 Molecular Formula: C62H79N13O7S Density: 1.26±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202284	(2S,4R)-1-((S)-2-(7-(4-(4-((9-((S)-1-Acryloylpyrrolidin-3-yl)-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)heptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-26-8	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1050.35 Molecular Formula: C57H71N13O5S Density: 1.34±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202285	(2S,4R)-1-((S)-2-(7-(4-(4-((9-((S)-1-Acryloylpiperidin-3-yl)-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)heptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-29-1	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1064.38 Molecular Formula: C58H73N13O5S Density: 1.33±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202286	(2S,4R)-1-((S)-2-(8-(4-(4-((9-((S)-1-Acryloylpiperidin-3-yl)-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)octanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-27-9	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1078.38 Molecular Formula: C59H75N13O5S Density: 1.32±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202287	(2S,4R)-1-((S)-2-(6-(2-(4-(4-((9-((S)-1-Acryloylpiperidin-3-yl)-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)acetamido)hexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-30-4	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1107.38 Molecular Formula: C59H74N14O6S Density: 1.35±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202288	(2S,4R)-1-((S)-2-(7-(2-(4-(4-((9-((S)-1-Acryloylpiperidin-3-yl)-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)acetamido)heptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-31-5	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1121.43 Molecular Formula: C60H76N14O6S Density: 1.34±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202289	(2S,4R)-1-((S)-14-(4-(4-((9-((S)-1-Acryloylpiperidin-3-yl)-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)-2-(tert-butyl)-4,13-dioxo-6,9-dioxa-3,12-diazatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	2768472-32-6	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1139.38 Molecular Formula: C59H74N14O8S Density: 1.37±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202290	PROTAC EGFR Degrader 3	2768472-28-0	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1092.43 Molecular Formula: C60H77N13O5S Density: 1.31±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202291	(2S,4R)-1-((S)-3,3-Dimethyl-2-(8-(4-(4-((8-(phenylamino)-9-((S)-1-propionylpiperidin-3-yl)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)octanamido)butanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide	2768472-36-0	VHL	EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1094.44 Molecular Formula: C60H79N13O5S Density: 1.31±0.1 g/cm3 Description: It is a potent PROTAC targeting EGFR mutants by optimizing covalent EGFR ligands.
	BPL-202292	N-(4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)-6-methyl-7-oxo-4-(2-phenoxyphenyl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2585561-28-8	CRBN	BRD2 BRD3 BRD4	Inquiry
Molecular Weight: 686.73 Molecular Formula: C38H34N6O7 Boiling Point: 959.5±65.0°C at 760 Torr Density: 1.418±0.06 g/cm3 Description: It is a novel pyrrolopyridone BET degrader based on the binding mode of the pyrrolopyridone BET inhibitor to BRD4 protein.

PROTAC Library