Azido-PEG6-NHS ester - CAS 2055014-64-5

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Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs.

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Molecular Formula
C19H32N4O10
Molecular Weight
476.48

Azido-PEG6-NHS ester

    • Specification
      • Related CAS
        1108750-59-9 (polymer)
        Purity
        ≥95%
        Solubility
        Soluble in DCM, DMF, DMSO, Water
        Appearance
        Pale Yellow or Colorless Oily Liquid
        Shelf Life
        0-4°C for short term (days to weeks), or -20°C for long term (months).
        Storage
        Store at -20°C, keep in dry and avoid sunlight
        Shipping
        -20°C (International: -20°C)
        IUPAC Name
        (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
        Synonyms
        Azido-PEG6-NHS;Azido-PEG6-CH2CO2-NHS; N3-PEG6-C2-NHS ester; N3-PEG6-CH2CH2COONHS Ester; 1-[(1-Azido-21-oxo-3,6,9,12,15,18-hexaoxahenicosan-21-yl)oxy]-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[(21-azido-1-oxo-4,7,10,13,16,19-hexaoxaheneicos-1-yl)oxy]-; 2,5-Dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
    • Properties
      • InChI Key
        WXKOAPGNZNSYPW-UHFFFAOYSA-N
        InChI
        InChI=1S/C19H32N4O10/c20-22-21-4-6-28-8-10-30-12-14-32-16-15-31-13-11-29-9-7-27-5-3-19(26)33-23-17(24)1-2-18(23)25/h1-16H2
        Canonical SMILES
        C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
    • Preparing Stock Solutions
      • ConcentrationVolumeMass1 mg5 mg10 mg
        1 mM2.0987 mL10.4936 mL20.9872 mL
        5 mM0.4197 mL2.0987 mL4.1974 mL
        10 mM0.2099 mL1.0494 mL2.0987 mL
Bio Calculators
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Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
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