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HQ461 - CAS 1226443-41-9

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HQ461 is a molecular glue that enhances CDK12-DDB1 interaction, triggering cyclin K degradation. This results in impaired CDK12 function, decreased phosphorylation of CDK12 substrates, downregulation of DNA damage response genes, and cell death.

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Molecular Formula
C15H15N5OS2
Molecular Weight
345.44

HQ461

    • Specification
      • Appearance
        Solid
        Storage
        Store at -20°C
Bio Calculators
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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
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