mPEG11-amine

 CAS No.: 854601-60-8  Cat No.: BP-500410  Purity: ≥95% 4.5  

mPEG11-amine is a monofunctional amine-terminated PEG linker used in ADC design to enhance hydrophilicity and pharmacokinetics. Suitable for single-point conjugation and surface modification.

mPEG11-amine

Structure of 854601-60-8

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Category
PROTAC Linker
Molecular Formula
C23H49NO11
Molecular Weight
515.64
Appearance
Pale Yellow or Colorless Oily Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO (10 mm)
Appearance
Pale Yellow or Colorless Oily Liquid
ShelfLife
-20°C 3 years powder; -80°C 2 years in solvent
Storage
Store at 2-8°C
Shipping
Room temperature, or blue ice upon request.
IUPACName
2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonyms
m-PEG11-amine; mPEG11-NH2; 2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratriacontan-34-amine; 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
Boiling Point
551.9±45.0 °C at 760 mmHg
Density
1.070±0.06 g/cm3 (Predicted)
InChI Key
SWAJVHMMXALQKJ-UHFFFAOYSA-N
InChI
InChI=1S/C23H49NO11/c1-25-4-5-27-8-9-29-12-13-31-16-17-33-20-21-35-23-22-34-19-18-32-15-14-30-11-10-28-7-6-26-3-2-24/h2-24H2,1H3
Canonical SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
Biological Activity
m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Gly-PEG3-endo-BCN | Bromo-PEG6-alcohol | Thiol-C9-PEG4-acid | Bis-PEG3-acid | t-Boc-Aminooxy-PEG12-NHS ester | Dodecaethylene glycol | Propargyl-PEG4-methylamine | Benzyl-N-bis(PEG3-Boc) | PC Azido-PEG11-NHS carbonate ester | Mal-PEG36-NHS ester | mPEG11-amine

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