mPEG9-amine

Size	Price	Stock	Quantity
--	$--	In stock

Size

Price

Stock

Quantity

$--

In stock

Purity

≥95%

Solubility

Soluble in DMSO (10 mm)

Appearance

Pale Yellow Oily Liquid

ShelfLife

≥ 2 years

Storage

Store at 2-8°C

Shipping

Room temperature, or blue ice upon request.

IUPACName

2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine

Synonyms

m-PEG9-amine; 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine; MPEG9-NH2; Methyl-PEG9-amine

Boiling Point

484.3±40.0 °C at 760 mmHg

Density

1.060±0.06 g/cm3 (Predicted)

InChI Key

FYQAZBUDEOSOFG-UHFFFAOYSA-N

InChI

InChI=1S/C19H41NO9/c1-21-4-5-23-8-9-25-12-13-27-16-17-29-19-18-28-15-14-26-11-10-24-7-6-22-3-2-20/h2-20H2,1H3

Canonical SMILES

COCCOCCOCCOCCOCCOCCOCCOCCOCCN

Biological Activity

m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

1.HDL functionality in South Asians as compared to white Caucasians.

Bakker LE1, Boon MR2, Annema W3, Dikkers A4, van Eyk HJ1, Verhoeven A5, Mayboroda OA5, Jukema JW6, Havekes LM7, Meinders AE1, Willems van Dijk K8, Jazet IM1, Tietge UJ3, Rensen PC9. Nutr Metab Cardiovasc Dis. 2016 Feb 19. pii: S0939-4753(15)30087-9. doi: 10.1016/j.numecd.2016.02.010. [Epub ahead of print]

BACKGROUND AND AIMS: South Asians have an exceptionally high risk of developing cardiovascular disease compared to white Caucasians. A contributing factor might be dysfunction of high density lipoprotein (HDL). We aimed to compare HDL function in different age groups of both ethnicities.

2.[Treatment of the old terrible triad of the elbow without operative history].

Zha YJ1, Jiang XY1, Gong MQ1. Beijing Da Xue Xue Bao. 2016 Apr 18;48(2):224-9.

OBJECTIVE: To introduce the surgical techniques and treating results of the old "terrible triad" of the elbow.

3.Impact of a systems engineering intervention on PMTCT service delivery in Côte d'Ivoire, Kenya, Mozambique: a cluster randomized trial.

Rustagi AS1, Gimbel S, Nduati R, Cuembelo MF, Wasserheit JN, Farquhar C, Gloyd S, Sherr K; with input from the SAIA Study Team. J Acquir Immune Defic Syndr. 2016 Apr 14. [Epub ahead of print]

BACKGROUND: Efficacious interventions to prevent mother-to-child HIV transmission (PMTCT) have not translated well into effective programs. Prior studies of systems engineering applications to PMTCT lacked comparison groups or randomization.

4.Comparison of mid-term haemodynamic performance between the BioValsalva and the BioIntegral valved conduits after aortic root replacement.

Wendt D1, Raweh A2, Knipp S2, El Gabry M2, Eißmann M3, Dohle DS2, Tsagakis K2, Thielmann M2, Jakob H2, Benedik J2. Interact Cardiovasc Thorac Surg. 2016 Apr 4. pii: ivw066. [Epub ahead of print]

OBJECTIVES: We retrospectively compared the haemodynamic performance of the BioValsalva (BV) and BioIntegral (BI) biological aortic-valved conduits in the aortic root position.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
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